Sulfaquinoxaline Sodium

It is an important, effective and commonly used coccidiostat throughout the world. For therapeutic purposes a dose of 0.5% in the feed is given. In drinking water, a dose of 0.043% is given for two durations each for 2 days with 3-5 days intervals, is satisfactory. Doses ranging from 0.025 to 0.033% over fairly long periods may be used as preventive medication. It is also active against E. acervulina in addition to E. necatrix and E. tenella. It exerts marked inhibitory effects on schizogony. When used at higher dose for long duration it produces toxic effects which include multiple hemorrhages in many organs accompanied by necrotic lesions in the spleen, hypoplasia of bone marrow and agranulocytosis. This compound has 6 days withdrawal premarketing requirement and eggs from treated birds should not be used for human consumption.